Although many observations have been carried out on the results of section of the trigeminal nerve in man for tic douloureux, little attention has heretofore been paid to its effect on the nose and the nasal mucosa. This is rather astonishing, as the present day conception of nasal pathology attributes many of its factors to reactions which can only be explained basically as a result of a disturbance of the nerve equilibrium, maintained in the nasal mucosa by its sensory and autonomic innervation. Especially, the wide range of so-called allergic reactions encountered daily with pathologic conditions of the nose should make advisable a morphologic study of noses which have been deprived of their first line of defense, their reaction to pain and irritation. Much of this pathologic change is attributable to mechanical irritation, and it is to be expected that the presence of such irritation, unnoticed by the patient, would
LEDERER FL, DINOLT R. INFLUENCE OF AVULSION OF THE TRIGEMINAL NERVE ON THE HUMAN NOSE. Arch Otolaryngol. 1943;37(6):768–784. doi:10.1001/archotol.1943.00670030783002
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