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Occurrence of Congenital Familial Deaf-Mutism in Six Children. Dr. Carl H. Christoph.
Heredity is a fifty-fifty proposition, in which both parents are responsible for the future disposition (anlage) of the child. According to Mendel's law, if the determining units, or genes, are similar, the offspring is a homozygote with respect to the specific character. If the units for a character differ—for example, if the father is deaf and the mother has normal hearing or vice versa—the child is a heterozygote with respect to that character. If the specific quality is distinguishable, or manifest, it is called dominant; if it is latent, or not distinguishable, it is called recessive. In the development of sex cells the paired anlage is divided (split), and a heterozygote would transmit the healthy factor to one-half his children and the abnormal factor to the other half.In the family reported on here both parents had normal
MUNDT GH. CHICAGO LARYNGOLOGICAL AND OTOLOGICAL SOCIETY. Arch Otolaryngol. 1943;38(3):300–306. doi:10.1001/archotol.1943.00670040313013
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