Malignant growths of the sinuses are not common. Of almost 400 cases of all types and locations of malignant neoplasms collected by one of us (J. H. A.), the sinuses were involved in only 3 cases, in 2 of which the growth originated in the antrum and in 1 in the left sphenoid sinus. The occurrence of malignant tumors of the sphenoid sinus is sufficiently rare to warrant the publication of a case.
Of 63 carcinomas and 7 sarcomas of the sinuses collected by Szende,2 none originated in the sphenoid sinus. According to Salinger,3 only 40 cases of malignant growths of the sphenoid sinus had been reported in the literature up to 1939. He pointed out, however, that as a rule carcinoma involving this sinus is diagnosed so late that it is difficult to determine exactly where the neoplasm arose. This suggests that a number of tumors which should have
HARDIE GC, AHRONHEIM CJH. PRIMARY CARCINOMA OF THE LEFT SPHENOID CAVITY. Arch Otolaryngol. 1943;38(5):497–501. doi:10.1001/archotol.1943.00670040516011
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