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December 1943


Arch Otolaryngol. 1943;38(6):594-596. doi:10.1001/archotol.1943.00670040617008

The accumulation of data relating to the genetic and environmental factors of otosclerosis is a groping maneuver in the search for the cause and the ultimate cure of this disease. It is admitted that it is a poor substitute for successful and illuminaing laboratory investigation. In the absence of the latter one would do well to follow the example and advice of Fowler,1 who urges the detailed reporting of cases of identical twins afflicted with otosclerosis.

The identical twin girls S. J. R. and M. A. R., the subjects of this report, were adopted by F. R. when only a few months old. In so far as known by F. R. the parents were not otosclerotic. The Wassermann reaction of the blood was negative, and the basal metabolic rate was slightly elevated for each twin.

My first contact with these children was in May 1928 when the foster father, a

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