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Article
August 1944

MÉNIÈRE'S SYNDROME: RESULTS OF TREATMENT WITH NICOTINIC ACID IN THE VASOCONSTRICTOR GROUP

Author Affiliations

NEW YORK
From the Ear, Nose and Throat Service of the Third (New York University) Surgical Division, Bellevue Hospital, and the Department of Otorhinolaryngology, New York University College of Medicine.

Arch Otolaryngol. 1944;40(2):101-107. doi:10.1001/archotol.1944.00680020133003
Abstract

In previous communications1 evidence has been produced to show: (1) that in cases of idiopathic Ménière's syndrome one of two vascular mechanisms is at work, a primary vasodilator and a primary vasoconstrictor mechanism, either of which can produce the characteristic picture; (2) that these two groups can be differentiated by means of an intradermal test with histamine; (3) that the treatment appropriate to one group is inappropriate and in fact deleterious in the other; (4) that therefore accurate grouping is a prime requisite for effective therapy. Further experience has only served to confirm these conclusions.

The satisfactory results obtained by desensitization to histamine in the primary vasodilator group have already been published.1b It is gratifying to be able to report that similar results continue to be obtained and that the improvement in the original cases is maintained.

This paper is concerned with the method and the results of treatment in

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