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The use of the new bacteriostatic agents to control infections of the nasal sinuses has been taken up with high hopes by both physician and patient because of the spectacular results obtained by their use for the control of infections in other parts of the body. The physician, in his eagerness to offer something for the treatment of sinus infections that would be better, or at least more rational, than nose drops, oral vaccines, inoculations and short wave diathermy, welcomed the advent of the new drugs with unrestrained enthusiasm. It is now three years since the first favorable report was published on the curing of sinus infections by spraying a solution of a sulfonamide compound into the nose. Rhinologists now should be in a position to take stock and estimate what benefits or damages have resulted from this mode of treatment that three years ago was hailed as a cure
WHALEN EJ. SULFONAMIDE COMPOUNDS IN THE TREATMENT OF INFECTIONS OF THE NASAL SINUSES. Arch Otolaryngol. 1944;40(6):481–486. doi:10.1001/archotol.1944.00680020611007
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