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Article
May 1945

OSTEOMYELITIS OF THE SUPERIOR MAXILLA: TREATMENT WITH PENICILLIN

Author Affiliations

PHILADELPHIA
From Otolaryngologic Service "B," Hospital of the Protestant Episcopal Church.

Arch Otolaryngol. 1945;41(5):351-352. doi:10.1001/archotol.1945.00680030380007
Abstract

It is well known that osteomyelitis of any bone of the skull is fraught with great danger to life, secondary to extension of the lesion throughout the cranium.

In a previous article on osteomyelitis,1 under the heading "Conclusions," the following statements were made:

One may expect any osteomyelitic lesion in the skull to cover pachymeningitis or to be complicated by an abscess of the brain. The first surgical step in the treatment of these two frequent complications of osteomyelitis is removal of the foci of infection....

The importance of general supportive treatment and measures to increase resistance cannot be overestimated.

Today otolaryngologists must add chemotherapy to their armamentarium.

I still maintain that it is always desirable, when possible, to limit the infection of bone to its orignal site. Extensions are often difficult to determine in early stages, and consequently in the past surgeons have been compelled to advocate radical surgical

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