Infections of the paranasal sinuses which are complicated by intracranial extension have always been considered serious and dangerous and usually have had a rather high mortality rate. Recently, the advent of chemotherapy, and especially that of penicillin, has modified the outlook in these cases. When these drugs are employed in the treatment of infections of the paranasal sinuses, one should remember that occasionally the effect on the clinical course and the picture of the disease may be confusing because, while the signs and the symptoms improve, fundamentally the pathologic process is getting worse. The case to be presented is especially interesting and instructive because it illustrates the foregoing observations and because it presents many unusual features. Although the case terminated fatally, it was tremendous both as to the amount of work done in combating the infection and as to the many interesting complications.
Briefly, there is presented a critically ill
CACIOPPO LT. MENINGITIS AND ABSCESS OF THE BRAIN DUE TO PANSINUSITIS. Arch Otolaryngol. 1945;42(1):47–50. doi:10.1001/archotol.1945.00680040061008
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