IT IS our purpose in this paper to present and discuss the treatment of a patient who had acute sinusitis which spread to the extraocular tissues and the blood stream, with possibly early involvement of the surrounding bone and irritation of the meninges.
Before the advent of penicillin therapy, acute sinusitis complicated by orbital cellulitis, bacteremia, thrombosis of the cavernous sinus or secondary meningitis was accompanied by a high mortality rate. The administration of sulfonamide compounds, with or without operative intervention, while of a certain value, frequently left much to be desired.
REPORT OF A CASE
A white man aged 23 entered the hospital with complaints of severe headaches and swelling of the left eye. The latter was of only four hours' duration. For one month he had suffered from attacks of frontal headaches, which he was told resulted from sinus disease. He was treated with a solution of a