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August 1946


Author Affiliations

From the Department of Pathology, Sea View Hospital.

Arch Otolaryngol. 1946;44(2):191-201. doi:10.1001/archotol.1946.00680060208008

ALTHOUGH there are many studies of laryngeal tuberculosis, most of these are based on clinical observations. The pathogenesis of laryngeal tuberculosis, over which there has been much controversy, cannot be studied from clinical findings alone, because organs other than the larynx must also be examined. This can be done only when the clinical findings are correlated with the pathologic studies.

In the course of autopsies by my colleagues and me, the larynx was routinely examined for gross and microscopic pathologic changes. An opportunity was thus afforded us to study the mode of development and the progression of laryngeal tuberculosis as well as its relationship to tuberculosis in other parts of the body.

INCIDENCE  During a period of five and one-half years there were 811 cases of tuberculosis which came to autopsy. Of these, 304 (37.5 per cent) showed evidence of laryngeal involvement. Although this is in accord with Lockard,1 who

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