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May 1947


Arch Otolaryngol. 1947;45(5):594-603. doi:10.1001/archotol.1947.00690010608010

THE LITERATURE of 1945 is notable for the many articles concerning the use of penicillin. Several reports were made by men in the armed services who had large numbers of patients under observation. There is still difficulty in obtaining journals from abroad.

CHEMOTHERAPY  Christierson1 reported on an unusually severe epidemic of otitis media which occurred in one of the naval training centers during the winter of 1943-1944. In 158 cases mastoidectomy was done, and in 29 there were grave complications. The patients received little help from the sulfonamide drugs but responded dramatically when penicillin was given. Complications included thrombosis of the lateral sinus in 10 cases, abscess of the brain in 1, facial paralysis in 3, otitic meningitis in 5, encephalitis in 2, labyrinthitis in 5 and erysipelas in 2. In 5 cases there was definite evidence of mastoiditis with roentgen evidence of destruction; in 1 of them this was