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December 1947

SYNDROME OF AVELLIS: A Review of the Literature and Report of One Case

Author Affiliations

From the Department of Otolaryngology of the South Baltimore General Hospital and the University of Maryland School of Medicine.

Arch Otolaryngol. 1947;46(6):773-778. doi:10.1001/archotol.1947.00690020790004

SINCE George Avellis,1 a German laryngologist, first published his series of 10 cases of this syndrome in 1891, less than 30 cases have been reported in the available literature.2

The syndrome of Avellis comprises a hemiparalysis of the larynx and soft palate on the same side, and, according to Jackson and Jackson,3 "there may be loss of pain and temperature sense on the opposite side, including the extremities, trunk and neck." This complex syndrome frequently results from a pathologic condition at the jugular foramen, though in some of the cases reported it was supposed to be of bulbar origin. Since the vagus nerve is closely associated with its neighboring cranial nerves at this level, numerous combinations and modifications are possible and have been described.4 It is not the object of this paper to discuss in detail the related syndromes or modifications but merely to review the reported cases of the