THROMBOPHLEBITIS OF THE CAVERNOUS SINUS ORIGINATING FROM ACUTE DENTAL INFECTION: Cure with Penicillin

SINCE GOODHILL¹ first published the report of a case of cavernous sinus thrombosis with recovery through the use of penicillin, there have been many other reports of the same nature.² The cases reported have been those of cavernous sinus thrombosis originating from various septic lesions over the face and in the nose. A case following infection of the antrum has been reported.³

In searching the literature, we found only 1 reported case of cavernous sinus thrombosis following extraction of teeth in which the patient was treated with penicillin.⁴ In view of the paucity of such reports, we believe that we are justified in reporting 2 such instances.

REPORT OF CASES  Case 1.—C. B., a 20 year old unmarried Lebanese woman, was admitted to the hospital on Dec. 2, 1945 in a semicomatose state. Three days previously she had experienced some pain in the region of her left upper central incisor,