MULTIPLE sclerosis was recognized as a clinical entity more than a century ago, and a voluminous literature has accumulated on its many and varied characteristics. Every physician is familiar with the effects of this disease on the central nervous system and certain of the cranial nerves. The ocular manifestations, for instance, are well known, and defects in the perimetric fields are of diagnostic importance. So it seems strange, indeed, that no serious attempt has been made to search for similar defects in the hearing range.
A number of isolated instances of deafness in cases of multiple sclerosis have been reported in the German literature. A thorough search leads back to 1856, when Valentiner1 described involvement of the auditory nerve in 1 case of his series. Two further cases were mentioned by Hirsch2 and Putzar,3 although the hearing disturbance in Putzar's case may be explained on the basis of an intercurrent
VON LEDEN H, HORTON BT. AUDITORY NERVE IN MULTIPLE SCLEROSIS. Arch Otolaryngol. 1948;48(1):51–57. doi:10.1001/archotol.1948.00690040058007
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