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Article
October 1948

STREPTOMYCIN BY TOPICAL APPLICATION IN TREATMENT OF CHRONIC SUPPURATIVE OTITIS MEDIA

Author Affiliations

MONTREAL, CANADA

Arch Otolaryngol. 1948;48(4):418-429. doi:10.1001/archotol.1948.00690040430004
Abstract

BECAUSE of the comparatively short time that streptomycin has been made available for clinical use in subduing infections of special otologic interest, except in very selected cases, it is not surprising that there is very little current literature available on the topical application of this antibiotic in cases of chronic suppurative otitis media.

One of the most comprehensive reviews published in recent years on otitis media (Dysart1) provided an extensive bibliography, covered the literature for 1945 and, as might be expected, contained no mention of the use of streptomycin topically, or in any other manner, in the treatment of otologic infections. Little of interest is found in this connection until the literature is reviewed for 1947. Several publications are of special interest with regard to the treatment of chronic suppurative otitis media.

REVIEW OF LITERATURE  Callum,2 whose valuable contribution was not intended to bear on the use of the antibiotics,

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