REPORTS of carcinomatosis of the meninges since Saenger's1 first publication in 1900 have been few. Although the condition occurs more frequently than the few reports would indicate, the number of reports including the pathologic changes occurring in the ear in this disease have been fewer (Schlittler,2 Wagener,3 Mayer,4 Hellmann,5 Brunner,6 Barth,7 Meller8). In the case which is described later the ears revealed many clinical and pathologic changes.
Carcinomatosis of the meninges is characterized clinically by symptoms of meningeal irritation and eventually by increase of intracranial pressure, followed by simultaneous appearance of symptoms of involvement of the cranial nerves and the spinal cord.
There is a dense accumulation of tumor cells in the subarachnoid space. The cells follow the flow of the cerebral spinal fluid and reach the subarachnoid sheaths of the cranial and spinal nerves. At the points where the nerves penetrate
GRABSCHEID E. CLINICAL AND PATHOLOGIC AURAL FINDINGS IN A CASE OF CARCINOMATOSIS OF THE MENINGES. Arch Otolaryngol. 1949;49(5):547–557. doi:10.1001/archotol.1949.03760110103008
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