THE INHALATION treatment of respiratory diseases has been known for centuries. Steam has been used by itself or with various volatile drugs, such as camphor or menthol, for many years. Shortly after Koch announced his discovery of the tubercle bacillus, someone advocated the inhalation of a culture of another organism to kill the tubercle bacilli in the lung. Following World War I, inhalation of chlorine gas was in vogue as a remedy for a cold in the head or the chest. The more recent use of inhalations of epinephrine for relief of asthma is known to everyone, and today almost every medical journal has an article about the inhalation of penicillin or streptomycin for some respiratory or general condition. It is only natural that the antibacterial drugs should be used by inhalation, for with this method they are delivered directly to the site of infection and in a concentration sufficient
DAVIS D. INHALATION OF PENICILLIN AND STREPTOMYCIN IN OFFICE PRACTICE. Arch Otolaryngol. 1949;50(2):156–171. doi:https://doi.org/10.1001/archotol.1949.00700010165002
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