EXCLUSIVE of systemic drugs, there are literally hundreds of nasal medicaments available for the treatment of infections of the upper respiratory tract. These fall into a number of different classifications, such as (a) vasoconstrictors, (b) vasodilators, (c) silver preparations, (d) oils, (e) antiseptics, (f) topical anesthetics, (g) volatile agents, inhalers, (h) powders, (i) estrogens, (j) intranasal vaccines, (k) cauterizing agents, (l) saline solutions, (m) bacterial lysates, (n) emulsions, (o) inhalants, (p) nasal jellies, (q) nasal sprays and others. In addition, of course, there are the various antibiotics and newer detergent agents. Of vasoconstrictors alone—drops, sprays, inhalants, and jellies—Kully1 estimated that there are several hundred on the market. As Fabricant2 has aptly pointed out, of drugs in the classes listed, "many are useful and worthy of clinical trials; some are of questionable value, while others are detrimental to the nose and sinuses."
In the relief and treatment of rhinitis due to
GRIESMAN BL. STUDY ON THE RANGE OF USEFULNESS OF A NEW DUAL FORM INTRANASAL MEDICAMENT. Arch Otolaryngol. 1949;50(2):190–199. doi:10.1001/archotol.1949.00700010199004
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