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Article
November 1949

HYDROGEN ION CONCENTRATION OF NASAL SECRETION IN SITU IN NEWBORN INFANTS

Arch Otolaryngol. 1949;50(5):616-617. doi:10.1001/archotol.1949.00700010630008
Abstract

IN PREVIOUS communications1 we reported that (1) the pH of nasal secretion in situ in clinically normal nasal passages of infants and children was found to range within the levels of 5.0 to 6.7, indicating a slightly acid state of secretion, and that (2) during the act of crying and hyperventilating the establishment of an alkaline nasal pH was a dominant finding in infants and very young children.

In the present investigation, an unusual opportunity to study the pH of nasal secretion in situ in a group of 13 newborn infants, ranging from 2 to 8 days in age, was provided by the nursery of a metropolitan hospital. The subjects were 7 male and 6 female infants. Although all 13 newborn infants had normal intranasal structures, 1 of the group had cerebral edema and another an occipital encephalocele. All the children were born by the vaginal route

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