Recognition of plasma cell tumors of the upper respiratory system and particularly of the accessory nasal sinuses has increased since attention has been called to their incidence by New,1 Claiborn,2 Jackson3 and others. The otolaryngologist finds these tumors of particular interest because of their occurrence in the upper respiratory tract and, especially, in the maxillary sinuses. The plasma cell tumor is generally considered to arise from the bone marrow although many cases of extraosseous origin have been reported. The classic multiple myeloma is thought to be a disease of the bone marrow or of the blood-forming structures generally, and, while the plasma cell tumors seem to be a phase in the developmental history of multiple myeloma, the cause and nature of these tumors are not definitely known and their exact relationship to multiple myeloma4 is not clear.
If the plasma cell tumor should be regarded as
PARKES M, BURTOFF S. PLASMA CELL TUMOR SIMULATING BILATERAL MAXILLARY SINUSITIS. Arch Otolaryngol. 1949;50(5):666–668. doi:10.1001/archotol.1949.00700010680014
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