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EVER SINCE it has been possible to make a diagnosis of atrophic rhinitis with ozena, physicians have sought means whereby this disease may be combated, or at least a treatment which would allay the unpleasant signs and symptoms of the condition. These methods have been basically hygienic, but, except for creating a state of cleanliness, they have been unsatisfactory in control of the disease.
Atrophic rhinitis with ozena tends to attack more than one member of a family and is more prevalent in females than in males. It shows no predilection for Russian Jews or for heavy smokers but is prevalent in the Near East—in Latins and Orientals. Although it is also encountered in the Negroes of the United States, it is not seen in the African Negro.
Atrophic rhinitis with ozena is the end result of an inflammatory disease of the mucosal parenchyma of the nose and the lining
ERSNER MS, ALEXANDER MH. OZENA: Evaluation of the Surgical Treatment. Arch Otolaryngol. 1949;50(6):805–812. doi:10.1001/archotol.1949.00700010820013
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