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Article
March 1950

ACUTE OTITIS MEDIA DUE TO KLEBSIELLA PNEUMONIAE TREATED WITH CHLORAMPHENICOL (CHLOROMYCETIN®)

Arch Otolaryngol. 1950;51(3):420-421. doi:10.1001/archotol.1950.00700020442012

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Abstract

In the early days of use of any new therapeutic agent it is important that clinical experiences be reported and shared. The various reports add up to a wealth of knowledge, which makes easier the choice of treatment in similar cases. For this reason it is believed that the presented case is of interest.

Chloramphenicol (chloromycetin®) is one of the newest of the antibiotics and is already known to have one of the widest ranges of usefulness. Even for so new a drug a voluminous literature attests to its efficacy in the treatment of diseases caused by gram-negative bacteria, rickettsias and certain viruses. Among diseases caused by gram-negative bacteria, limited clinical study reveals that chloramphenicol is effective in the treatment of pneumonia caused by Klebsiella pneumoniae (Friedländer's bacillus). As far as can be ascertained, this is the first reported instance of its use in middle ear suppuration due to this

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