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Article
July 1950

TREATMENT OF JUVENILE PAPILLOMA OF THE LARYNX WITH RESIN OF PODOPHYLLUM: A Preliminary Report

Author Affiliations

OAKLAND, CALIF.; SAN FRANCISCO
From the Division of Otolaryngology, Department of Surgery, Stanford University School of Medicine (Dr. Kohlmoos and Dr. McNaught).

Arch Otolaryngol. 1950;52(1):82-87. doi:10.1001/archotol.1950.00700030101011
Abstract

PAPILLOMA of the larynx in children is an extremely distressing disorder. Obstructive symptoms and the resulting severe infections of the respiratory tract frequently increase in spite of continuous care. Ferguson and Scott1 reviewed 15 of their cases from 1933 to 1942 in which death resulted from asphyxia in 2 and laryngeal diphtheria developed with ensuing death in 1. A great variety of treatments, including irradiation and hormone therapy, have been tried without consistent good results.2 The disorder has been considered to be self limited, with recurrences, and eventually to cease. Many have reached the conclusion that the only therapy indicated is insurance of adequate airway by repeated removal of the lesions and tracheotomy if necessary.3

Long hospitalization and repeated instrumentation are necessary with this therapy. Extension or implantation of the papilloma low in the trachea with ensuing obstruction is a serious problem and cause of great frustration to the one

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