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Article
January 1951

HISTOLOGY AND HISTOGENESIS OF CHOLESTEATOMA OF THE MIDDLE EAR AND MASTOID

Author Affiliations

ROCHESTER, MINN
Dr. Begley is a Fellow in Otolaryngology and Rhinology, Mayo Foundation.; From the Section on Surgical Pathology (Dr. McDonald) and the Section on Otolaryngology and Rhinology (Dr. Williams), Mayo Clinic.

AMA Arch Otolaryngol. 1951;53(1):41-52. doi:10.1001/archotol.1951.03750010060004
Abstract

ALTHOUGH cholesteatomas of the middle ear and mastoid are of relatively common occurrence, and much about them has been observed and written during the past hundred years, their name is a misnomer, their nature is often misunderstood and the theories of their origin are confusing and contradictory. Of the almost universally accepted "invasion theory" of the cause of aural cholesteatomas, Diamant1 said:

When a particular view (of a hypothetic nature) regarding cause and effect has once been established in the literature, particularly in textbooks, it is liable, owing to faith in authorities, to get firmly rooted in the consciousness.... The adherence to Bezold's hypothesis as the sole alternative must be ascribed to inertia and to innate reluctance to abandon "knowledge" acquired from standard books.

Because of this existing confusion and dogma, and because it is felt that evidence exists which may help to clarify the pathogenesis of cholesteatomas, and

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