In the quest for an ideal ear drop for the common chronic otorrhea, the gamut of chemical agents has been tried, from the time-honored boric acid-alcohol solution to the sulfonamides, glycerite of hydrogen peroxide and the antibiotics. Although each one gives a certain degree of clinical satisfaction, there is still room left for improvement. The literature on the subject is so voluminous that one is at a loss concerning the merit of one chemical over that of the other.
The reports on the treatment of chronic purulent otitis media by Brown and Owen1 with glycerite of hydrogen peroxide; by Loeb2 and Rawlins3 with penicillin, and by Harris, Kilham and Finland4 with streptomycin were indeed very encouraging. Assuming that the separate use of these three agents has brought about a high percentage of cure, why not use them all in a shotgun mixture so that they would
VICENCIO AB. TREATMENT OF CHRONIC OTITIS MEDIA WITH A MIXTURE OF GLYCERITE OF HYDROGEN PEROXIDE, STREPTOMYCIN AND PENICILLIN. AMA Arch Otolaryngol. 1951;53(1):87–88. doi:10.1001/archotol.1951.03750010106009
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