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March 1951


AMA Arch Otolaryngol. 1951;53(3):319-332. doi:10.1001/archotol.1951.03750030078010

OTOSCLEROSIS  SMITH1 reviews the recent literature on otosclerosis. He investigated the effect of pregnancy on 73 women with otosclerosis observed at the New York Eye and Ear Infirmary. Thirty-seven, 37 per cent, of these subjects gave a history of their deafness being initiated, or, if present, increased by pregnancy. Only 21 women, 29 per cent, gave a history of familial deafness. He agrees with most other recent investigators that eugenic measures of controlling otosclerosis are not likely to be very effective. He reports one unusual case in which the hearing was temporarily improved during each of two pregnancies. He does not believe that termination of early pregnancy to prevent further progression of deafness is in general justifiable.Fowler,2 in his study of the blood chemistry of patients with clinical otosclerosis, found no significant changes in phosphatase values. He points out that skeletal involvement must be considerable to elevate