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September 1951


Author Affiliations

Dr. Plotz is Associate Clinical Professor of Medicine, State University of New York, Medical Center at New York.

AMA Arch Otolaryngol. 1951;54(3):273-278. doi:10.1001/archotol.1951.03750090044004

THE ASSOCIATION of hoarseness and heart disease is a well-defined, although uncommon, clinical syndrome. Nevertheless, this combination has not received the attention it merits in the laryngological literature, either text or periodical. Two illustrative cases will, therefore, be included in this article, together with a brief resume of the literature and a discussion of the pathogenesis.

The first description of this condition was given by Ortner in 1897.1 Since then a number of articles on the subject have been published, but the first allusion to this association in a journal of laryngology was in the report of New and Childrey in 1932.2

The syndrome consists of hoarseness and enlargement of the heart. The hoarseness is the result of palsy of the left recurrent laryngeal nerve, and laryngoscopy may reveal any grade of defective movement of the left vocal cord, from mere sluggishness to complete paralysis. Involvement of the

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