SINCE the advent of sulfonamides and the antibiotics of the past decade, the decrease in otorhinogenous intracranial complications has been remarkable. Despite this fact, however, reports of such complications are still appearing in the literature with fair regularity.
The reasons for the continuation of these occasional complications are varied and speculative. Many authors believe that many otorhinogenous infections still must be treated with adequate surgical drainage in addition to sulfonamides or antibiotics to safeguard against intracranial complications. Maxwell1 stated that common causes for failure in the treatment of the original infection are (1) starting the use of specific drugs too late; (2) inadequate therapy, either by too small amounts of chemotherapeutic agents or by timid and intermittent administration of these agents, and (3) use of nonspecific therapy, i. e., treating an infection with a nonspecific agent, emphasizing the need for routine cultures.
Maxwell1 stated that in
JAMES L. BALDWIN. INTRACRANIAL COMPLICATIONS IN OTOLARYNGOLOGY. AMA Arch Otolaryngol. 1951;54(6):723–733. doi:10.1001/archotol.1951.03750120116016