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February 1952


Author Affiliations

From the Departments of Surgery and the Division of Otolaryngology of Stanford University Medical School.

AMA Arch Otolaryngol. 1952;55(2):210-217. doi:10.1001/archotol.1952.00710010219012

THE HISTOLOGIC entity most commonly called cylindroma, but known also by a variety of other names (adenoid cystic basal cell carcinoma, adenocarcinoma of cylindroma type, adenomyoepithelioma, and cellular mixed tumor) is encountered in many branches of surgery. The so-called cylindroma occurs wherever salivary or mucous glands are found. Despite its ubiquitous nature, however, confusion exists as to its proper genesis, classification, and clinical picture.

Billroth1 first used the term cylindroma in 1856 to describe a tumor which had arisen from the mucous glands of the accessory nasal sinuses, and penetrated into the orbit.2 He referred to a tumor composed of glossy translucent cylinders of hyaline connective tissue between which ran a network of tumor cells.3 Since then, similar tumors have been frequently recognized in the oral cavity, nasopharynx, and salivary glands, as well as in the skin, larynx, and bronchi.

The lack of unanimity of opinion regarding

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