MUCH has been written about otitis media in children, but very little about it in infants. In the light of the newer concepts of antibiotic therapy, it is felt that diseases of the middle ear in infants require newer evaluation, newer clinical concepts, and different treatment. In the past, clinical attention in the search for a diagnosis in infants who showed marked irritability, sleeplessness, diarrhea, poor appetite, and increases in temperature from 100 to 101 F. was directed to the gastrointestinal tract for the cause. Although it is known that middle ear infections can be the forerunner of gastrointestinal symptoms, the infants' ears were not examined thoroughly until they began to discharge spontaneously, after which the aforementioned symptoms were relieved. Other infants and children with suppurative otitis media were treated with antibiotics and sulfonamides without myringotomy. This resulted in a return to normal temperature and an absence of clinical complaints,