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Article
September 1952

PAROTID GLAND TUMORS: Study with Reference to Origins

AMA Arch Otolaryngol. 1952;56(3):277-289. doi:10.1001/archotol.1952.00710020297006
Abstract

ALTHOUGH in recent years an increasing number of competent investigators have become convinced that the so-called mixed tumors of the parotid gland are of purely epithelial origin, there is no real unanimity concerning the histogenesis or the structure of these tumors.

Despite the fact that the epithelial-appearing portions of these neoplasms assume a variety of histological appearances, as, for example, nearly normal-looking salivary tissues, atypical glandular tissue, solid epithelial formations, epithelial formations with cystic spaces, and carcinoma especially of the basal-cell type, the controversy is not due to this pleomorphism. It is, rather, dependent upon the mesodermal-appearing portions of the growths and most particularly upon the "cartilaginous" structures which are so often present. It is this "cartilage" which is the crux of the problem. Is it, or is it not, true cartilage? If it is true cartilage, it has most likely arisen from mesenchymal elements, in which case the growths

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