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TUMORS OF THE NOSE AND PARANASAL SINUSES
FRIEDMANN1 decribes his experience with the Papanicolaou technique of exfoliative cytology as applied to the diagnosis of tumors of the throat, nose, paranasal sinuses, and ear. Secretions and specimens were collected on cotton applicators. Specimens collected at the time of direct laryngoscopy proved more suitable than material collected at indirect laryngoscopy. The material obtained was smeared on glass slides, and the wet slide was dropped immediately into fixative (equal parts of absolute alcohol and ether).Friedmann's report is based on the examination of about 1,300 smears in 212 cases in which the presence of malignant disease was suspected. False negative results were reported in 2.3%, and false positive results were reported in 4.2% of the cases. The method is of value and can supply useful information in the following instances: (1) when biopsy is impossible because of the
FIGI FA, DEVINE KD. TUMORS OF THE NOSE AND THROAT. AMA Arch Otolaryngol. 1952;56(6):644–662. doi:10.1001/archotol.1952.00710020669010
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