THE WIDESPREAD use of corticotropin (ACTH) and cortisone in various fields and the particular benefits which ophthalmologists1 have witnessed, together with reports of the response of otosclerosis,2 led to the belief that chronic otitis media might be another condition in which to try cortisone.
The primary aim of the studies to be reported was to determine the effects of cortisone (Cortone) drops in chronic otitis media, and my attention was directed to whether cortisone would alter or suppress the secretion, heal the perforation, destroy granulation tissue, or produce any other response.
Fourteen patients with chronic otitis media were treated with cortisone ear drops. Most had previously received local and parenteral medication of some sort intermittently without any response. All the patients were seen for the first time during May and June, 1952, and repeated examinations were done two to four months after medication for the purpose of noting
TIONLOC RC. EFFECTS OF CORTISONE IN CHRONIC OTITIS MEDIA: A Preliminary Report. AMA Arch Otolaryngol. 1953;58(1):50–54. doi:10.1001/archotol.1953.00710040067006
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