IN 1949 and 19501 I reported in some detail the results of an investigation along nutritional lines on a series of 87 cases of Ménière's syndrome. From this investigation the following conclusions were drawn:
That patients with Ménière's syndrome present two distinct clinical pictures, which are readily distinguishable.
That many patients experience both kinds of attack and thus present a mixed clinical picture.
That patients can be divided by means of a histamine skin test into three groups instead of the two previously described: one in which the mechanism is primarily vasoconstrictor; another, in which the mechanism is vasodilator, and a third, an intermediate group, in which the attacks are now one, now the other.
That these three groups correspond to the three clinical groups mentioned.
That all three groups show signs of chronic severe deficiency of the vitamin B complex.
ATKINSON M. MÉNIÈRE'S SYNDROME: Further Observations on Vitamin Deficiency as Causative Factor. AMA Arch Otolaryngol. 1953;58(2):127–132. doi:10.1001/archotol.1953.00710040146002
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