OTOSCLEROSIS, its causes and cure, has consumed the energies of many scientific investigators in various disciplines of medicine without success. The embryologist, the histologist, the pathologist, the clinician, the surgeon, have all, individually and collectively, exerted themselves in seeking to find a cure for this heretofore unexplained malady. Otosclerosis, causing chronic progressive hearing loss, affects the destiny and serviceability of many millions of persons everywhere. New concepts, new hypotheses, new explanations for otosclerosis, accepted originally with enthusiasm, have one by one volatilized and left otologists with the stark reality of this unexplained disease. The historical aspects of the study of the condition have been reiterated so often that it would serve no purpose to do so again. The constant search for a medical or surgical cure has reached a culmen through the tireless, ceaseless efforts and contributions of many scientists. Their limitless ingenuity and investigative brilliance have been the greatest
ANGELUSCHEFF Z, COLEMAN LL. ULTRASONICS AND OTOSCLEROSIS: A New Concept of Its Origin. AMA Arch Otolaryngol. 1953;58(4):398–404. doi:10.1001/archotol.1953.00710040420002
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