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November 1953


Author Affiliations


AMA Arch Otolaryngol. 1953;58(5):623-634. doi:10.1001/archotol.1953.00710040649010

THE ARTICLES on otitis media and its complications which appeared in 1952 are listed under several headings. The reviewer's comments have been placed in brackets.

CHEMOTHERAPY AND BIOTHERAPY  Lewis and Hewlett1 (London, England) treated a group of 25 children with acute otitis media by daily injections of penicillin. They treated a similar group with chlortetracycline (Aureomycin) and another with chloramphenicol (Chloromycetin). They found that it was very hard to get children to take chlortetracycline or chloramphenicol, especially those between 1 and 4 years of age. They found that in the children who took the drugs regularly the results were similar. Cultures were made and sensitivity tests were done routinely. When they found that an organism was insensitive to a drug used the drug was changed. Two mastoid operations were necessary in the entire group. In order to compare a control group, who had no treatment, a group of 23

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