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Article
February 1954

A SAFER ANESTHETIC FOR PERORAL ENDOSCOPY: Preliminary Report

Author Affiliations

OMAHA
From the Surgical Services of the Creighton University School of Medicine and the Veterans Administration Hospital.

AMA Arch Otolaryngol. 1954;59(2):195-197. doi:10.1001/archotol.1954.00710050207011
Abstract

THE IMPORTANCE of bronchoscopy and bronchography in the diagnosis of pulmonary disease is well recognized. It is unfortunate that these extremely valuable diagnostic procedures are attended by a small but definite mortality rate. Small as the risk may be, it is, nevertheless, something which must be considered when these procedures are recommended. It is even more unfortunate when one considers that the danger is almost entirely due to the anesthetic drugs used rather than to the danger of the manipulations in the procedure itself. Efforts to reduce this mortality rate by improving the safety of the anesthetic agents are therefore well advised.*

Since the anesthetic effect of antihistaminic drugs has been under investigation,† it was believed that it would be of interest to learn whether this effect could be profitably exploited to make peroral endoscopic procedures safer. This is a report on the results of my early experiences with tripelennamine

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