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July 1954


Author Affiliations

From the Institut d'Anatomie Pathologique (Director, Professor Gery) and the Clinique Oto-Rhino-Laryngologique (Acting Director, Dr. Wild), of the Faculty of Medicine of Strasbourg.

AMA Arch Otolaryngol. 1954;60(1):37-48. doi:10.1001/archotol.1954.00720010040004

THE PARTICULAR origin of the olfactory mucosa is well-known. Both the epithelial and the nervous portions originate from the same thickening, which forms above the rudimentary mouth to the detriment of the epiblast. It is therefore a rare, but no less unquestionable, example of the epiblastic origin of certain nerve cells.

One might expect, a priori, to encounter in the nasal fossae tumors bearing a more or less marked resemblance to those originating in the central nervous system. This fact has been definitely established. It is to Louis Berger that credit is due for the identification of the nerve tumors of the olfactory organ.

Berger1 described in 1924, at the Institut d'Anatomie Pathologique de Strasbourg, a tumor of the nasal fossae, observed in a 50-year-old man, of which the histological structure was reminiscent of that of the embryonic nerve tumors, called "nevraxo-epitheliomas" by P. Masson and characterized by the

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