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March 1955

Plasmocytoma of the Nasal Cavity

Author Affiliations

Olympia, Wash.

AMA Arch Otolaryngol. 1955;61(3):277-279. doi:10.1001/archotol.1955.00720020292002

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A plasmocytoma is a growth composed of plasma cells and is similar to a lymphoma in its gross characteristics. A plasma cell is a cell with a nucleus situated at one pole and with the nuclear chromatin having a spoke-like arrangement. The cytoplasm is basophilic, and there is a pale area near the nucleus, which contains a diplosome. Eosinophilic granules and crystals appear in the protoplasm when the cell is degenerated or during certain virus infections. These have been described as Russell's or Una's bodies. Plasmocytomas, under certain conditions, may assume malignant characteristics and, under these circumstances, they grow rapidly and infiltrate the surrounding structures. Plasmocytomas are seen in the nose, turbinates, and nasopharynx, where they appear as infiltrative or pedunculated growths covered with a reddish mucosa. Plasma-cell myeloma of the bone marrow and plasmocytomas have similar cell structure but are entirely different in their clinical course and gross appearance.

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