SMOOTH muscle tumors are very rarely encountered in the upper respiratory tract. Eggston and Wolff,1 in their textbook "Histopathology of the Ear, Nose and Throat," state that a few cases of leiomyoma in the esophagus and trachea have been reported; however, I was unable to find a single case of leiomyoma of the trachea recorded in the literature.
Several theories have been advanced as to the actual origin of leiomyomata. It seems probable that they arise from smooth muscle itself, but there are those who believe them to originate from the musculature of bloodvessel walls.2
Microscopically, leiomyomata are dense, hard masses which on section exhibit cystic spaces. The latter result from disintegration of the tissue due to the scarcity of blood vessels.
Microscopically, leiomyomata are composed of smooth muscle fibers arranged in parallel rows. Bundles interlace in every direction. These bundles are embedded in an abundant stroma of
DORENBUSCH AA. LEIOMYOMA OF THE TRACHEA: A Case Report. AMA Arch Otolaryngol. 1955;61(4):470–471. doi:10.1001/archotol.1955.00720020486015
Monkeypox Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.