Esophageal pathology has rarely received the attention it deserves. Its symptoms have frequently been attributed to cardiac, pulmonary, gastric, and gall-bladder disease. Perhaps this is because lesions in the esophagus may be secondary, as we shall see, to diseases of the above organs. It should be of fairly general interest to call attention to a little-known entity, which is probably much commoner than is realized. This entity is the irritative inflammatory change of the esophagus produced by the reflux of acidpeptic gastric contents into the esophagus from a variety of causes. This is not a new observation and an excellent summary of the literature has been published by several authors.*
The unfortunate chain of events involved deserves our serious consideration because relatively innocuous symptoms may insidiously lead to considerable morbidity, disability, and even mortality. These eventualities may be averted by timely and simple intervention in the early stages. However, even
CRANMER LR. Esophagitis and Stricture from Regurgitation. AMA Arch Otolaryngol. 1955;61(6):611–615. doi:10.1001/archotol.1955.00720020629001
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: