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June 1955


Author Affiliations

From the Department of Surgery, Woodlawn Hospital, and the Department of Oral and Maxillofacial Surgery (Dr. Sarnat), and the Division of Oral Pathology (Dr. Weinmann), University of Illinois, College of Dentistry.

AMA Arch Otolaryngol. 1955;61(6):654-657. doi:10.1001/archotol.1955.00720020672010

A CASE of lymphosarcomatosis appeared to be of interest for the following reasons: 1. The only initial symptom of the disease occurred first in the gingiva and spread subsequently in the adjacent mucosa of the hard palate. After approximately 10 months, systemic manifestations appeared. 2. While the disease was localized to the oral cavity, three biopsy specimens taken at intervals were examined microscopically. The first two were diagnosed as nonspecific chronic inflammation. Since the majority of gingival lesions are of a nonspecific chronic inflammatory nature, it was not surprising that such a diagnosis was made. The real nature of the changes was recognized only after the third biopsy. In view of this information reexamination of the first two biopsy specimens confirmed the diagnosis of lymphosarcoma.


Clinical History (August, 1953)  Present Complaint.—A 35-year-old white housewife (P. R.) saw her dentist in April of 1953, complaining of