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July 1955


Author Affiliations

Hagerstown, Md.
From the Department of Pathology, University of Maryland, School of Medicine, Baltimore.

AMA Arch Otolaryngol. 1955;62(1):81-83. doi:10.1001/archotol.1955.03830010083012

THE TUMOR generally referred to as granular-cell myoblastoma, while usually found in locations where striated muscle is normally present, is not uncommonly found in areas where this type of muscle is not ordinarily found.

The commonest locations of this type of tumor are in the skin and tongue. Other frequent sites are extremities, head, trunk, larynx, and gums. Less frequent locations are uterus, vulva, bladder, orbit, appendix, perianal region, stomach, esophagus, omentum, and retroperitoneum. In 1945 Crane and Tremblay1 reported on the various locations of 162 cases of granular-cell myoblastoma. Murphy, Dockerty, and Broders2 in 1949 reviewed all the cases which had been reported up to 1947. To these, they added 10 of their own. More recently, Stout3 reviewed the location and histology of 136 examples of myoblastoma.

Its widespread distribution in tissues unrelated to the skeletal system excites the wonder of those who would explain