For over a hundred years chemists have been attempting to use the powerful germicidal effect of chlorine as an agent in controlling infection. Recently a new group of agents have been developed, consisting of modified buffered hypochlorous acid derivatives, which appear to yield their active chlorine almost quantitatively as hypochlorous acid. Chemically they can be classified as monoxychlorosene* derivatives. This paper is a preliminary report of the use of Clorpactin WCS-90 in otolaryngology.
Clorpactin is produced in various strengths, consisting of white, water-soluble powders or granules, whose dilute solutions are powerful germicides, fungicides, and virucides, yet are nontoxic and nonirritating when used in therapeutic dosages. These hypochlorous acid derivatives form dilute solutions with pH's varying from a highly acid 4.2 to substantially neutral, and are highly buffered. They are excellent oxidizing agents, effective deodorizers, and exhibit pronounced wetting, penetrating, and detergent properties. The grade of Clorpactin used in this
ZWERLING M. Clorpactin WCS-90: A New Antiseptic: Preliminary Report. AMA Arch Otolaryngol. 1955;62(2):157–158. doi:10.1001/archotol.1955.03830020039008
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