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August 1955

Granulomatous Polyp of the Larynx Following Intratracheal Anesthesia

Author Affiliations

Beverly Hills, Calif.

AMA Arch Otolaryngol. 1955;62(2):182-186. doi:10.1001/archotol.1955.03830020064012

Granulomatous polyp of the larynx is an inflammatory tumor caused by trauma during endotracheal anesthesia. This condition was first reported by Clausen22 in 1932. It occurs only in the adult larynx, may be unilateral or bilateral, is always due to trauma, and has a constant location on the laryngeal aspect of the vocal process of the arytenoid cartilage. In its early phase the polyp is always infected; hence histologically it is a pyogenic granuloma. At this time it measures between 5 and 9 mm. in diameter. Within a few weeks the epithelium of the adjacent structures gradually covers the polyp. As time passes the stroma of the tumor becomes fibrotic, new blood vessels form, and the original pyogenic granuloma is transformed into an angiofibroma. The pale-grayish polyp is now cherry-red or purplish-red according to the degree of vascularity present. As a result of these changes the tumor is much