According to Jackson and Jackson,1 statistics show that malignant disease of the larynx is uncommon before 25 years of age. Most of the cases occur in patients over 40. However, they state that it has occurred in a patient 3 years of age. This, however, is an exceedingly rare exception to the rule. Their statistics showed that of 688 cases of malignant disease of the larynx 635 occurred in men (92.3%) and 53 (7.7%) were in women.
Walsh and Beamer2 reported two cases of epidermoid carcinoma of the larynx occurring in two children with papilloma of the larynx: a boy of 12 and a girl of 11.
Negus,3 in reporting on a series of cases of carcinoma of the larynx (93 intrinsic and 94 extrinsic), found in his series of 93 intrinsic cases 90 men and 3 women. The youngest patient was a woman of 26 years
WEINSTEIN S. Cancer of the Larynx: Report of a Case in a Negro Woman Nineteen Years of Age. AMA Arch Otolaryngol. 1955;62(4):380–383. doi:10.1001/archotol.1955.03830040034005
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