Respiratory-tract allergy and pathological variations due to associated infection occur more frequently than generally recognized. It is now a well-established fact that allergy predisposes to and aggravates many diseases of the upper and lower respiratory tract. Recent surveys* relating to the frequency of allergy as an etiologic factor or as a complication in diseases of the ear, nose, and throat show 70%-80% of all office patients to be allergic. Kern4 states that the respiratory tract is the site of the commonest, the most diversified, and some of the severest manifestations of hypersensitivity. Respiratory-tract allergy encompasses such a vast field that only the theoretical high lights and important clinical applications will be included.
The primary factor in the clinical aspect of the allergic reaction and the fundamental concept with which we are concerned is that the various parts of the respiratory tract be considered as shock organs. It is at
DINTENFASS A. Significance of Allergy in Persistent Respiratory Infection. AMA Arch Otolaryngol. 1956;64(3):171–177. doi:10.1001/archotol.1956.03830150001001
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