SINCE THE advent of chemotherapeutics and antibiotics and other "wonder drugs," a certain complacency had crept into the minds of physicians and patients alike about the seriousness of a chronic ear discharge. While one may say that the prognosis in acute ear infections has markedly improved by adequate therapy with antibiotics, the chronic ear conditions were not influenced by these medications. As a matter of fact, inadequate antibiotic therapy has contributed to masking of the symptoms until the pathology was more advanced, and the manifestations of mastoid disease are now more variegated than in the days prior to the usage of the above drugs. Also, it is now fairly well established that in mastoid infection the bony changes like osteitis and periosteitis or osteomyelitis induce thrombosis of the blood vessels that supply the mastoid bone, and these thrombosed vessels prevent the dissemination of the medication to the local foci of
Achar MVR. CHRONIC MASTOIDITIS CAUSING FACIAL NERVE PARALYSIS, HYPOGLOSSAL NERVE PARALYSIS, AND ABSCESS IN THE NASOPHARYNX. AMA Arch Otolaryngol. 1956;64(6):543–551. doi:10.1001/archotol.1956.03830180093015
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