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December 1957

Prevention of Adverse Effects of Streptomycin on the Ear

Author Affiliations

Nara-Ken, Japan
Department of Otorhinolaryngology, Osaka Communications Hospital.

AMA Arch Otolaryngol. 1957;66(6):673-678. doi:10.1001/archotol.1957.03830300053005

How many years has it been since Waksman discovered streptomycin? And how many years has it been since the adverse after-effect of streptomycin on hearing ability became known?

Research in antibiotics having advanced, when will it be before an antibiotic without adverse after-effects is discovered. When I think of today it is difficult for me at times to put myself wholeheartedly into my work. But, sad to say, we who have direct contact with the patients are in the position of responsibility for eliminating, so far as possible, these adverse after-effects, hoping that the new antibiotic may be found in the near future. Until that day research must be continued with unfailing zeal. I have learned from a journal that new drugs have been discovered that are similar to streptomycin, without their adverse after-effects, but they are said to be in an experimental stage. I hope that the discovery of

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