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January 1958

Serous Otitis Media: Treatment with Injectable Trypsin

Author Affiliations

Norristown, Pa.

AMA Arch Otolaryngol. 1958;67(1):24-27. doi:10.1001/archotol.1958.00730010028005

Secretory otitis media has presented problems in its management as evidenced by the reports in medical literature and by our own everyday experience in dealing with this entity.

Many cases of secretory otitis media respond to simple management, utilizing a single myringotomy plus politzerization of the Eustachian tube. However, there are many cases which become protracted, requiring multiple myringotomies repeated frequently; they then become chronic cases of secretory otitis media. Therefore time and the problem of management differentiate the acute from the chronic cases.

Because management of the chronic cases has posed some problems, suggestions have been made regarding their solution. Hoople et al.1 recommended politzerization in addition to myringotomy. Autoinflation by the patient has been suggested to maintain drainage through the myringotomy wound. Armstrong2 has suggested the use of an indwelling polyethylene tube inserted through the membrana tympani, where it is allowed to remain until the condition

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